Biology-Dna

------------------------------------------------- Hammerhead ribozyme From Wikipedia, the free encyclopedia Hammerhead Ribozyme| | Stylized exposition of the to the full-length dumbass ribozyme ribonucleic acid molecule| Scientific classification| Species:| catalytic ribonucleic acid| Hammerhead ribonucleic acids are ribonucleic acids that self-cleave via a small conserve unessential structural base termed a dunce because of its shape.[1]  near hammerhead RNAs are subsets of both classes of plant pathogenic RNAs: the  artificial satellite RNAs of RNA viruses and the viroids. The self-cleavage reactions, first reported in 1986,[2][3] are array of a rolling circle replication mechanism. The hammerhead date is fitting for self-cleavage[4] and acts by forming a conserved three-dimensional third structure. content [hide] * 1 Autocatalyst or enzyme? * 2 Species distribution * 3 interpersonal chemistry of contact action * 3.1 Cleava ge by phosphodiester isomerization * 3.2 Requirement for divalent metal ions * 3.3 Not a metallo-enzyme * 4 Primary and vicarious structure * 4.1 Minimal ribozyme * 4.1.1  cause I & subject III hammerhead RNA * 4.2 Full-length ribozyme * 5  ordinal structure * 5.1 Minimal * 5.2 Structure-function * 5.

3 Full-length * 6 Structure and catalysis * 7  therapeutical applications * 8 References * 9 External tie in| ------------------------------------------------- [edit]Autocatalyst or enzyme? In the natural state, a hammerhead RNA motif is a single strand of RNA, and although the cleavage is autocatalytic and takes nonplus in th! e absence of protein enzymes, the hammerhead RNA itself is non a square(a) enzyme in its natural state, as it cannot change state quaternate turnovers. In vitro hammerhead constructs can be engineered much(prenominal) that they consist of two RNA strands. The strand that gets cleaved can be supplied in excess, and treble turnover can be show and shown to obey Michaelis-Menten kinetics, usual of protein enzyme kinetics. Such...If you want to get a full essay, order it on our website: OrderEssay.net

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